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KMID : 1123920100240030401
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Korean Journal of Oriental Physiology and Pathology
2010 Volume.24 No. 3 p.401 ~ p.409
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Effects of BojungIkkiTang-Gamybang on Protective of Cell Death and Anti-Oxidative in C6 Glioma Cell
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Hwang Gui-Seong
Kim Hyung-Woo
Choi Chan-Hun
Jeong Hyun-Woo
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Abstract
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This study was designed to investigate the effects of BojungIkkiTang-Gamybang freeze dried powder (BITG) on proliferauion, protective of cell death induced by chemicals such as paraquat, hydrogen peroxide etc and anti-oxidative effects in C6 glioma cells. In our results, BITC accelerated proliferation rates of C6 cells in vitro. In addition, protective effects on cell death induced by paraquat and hydrogen peroxide. And, BITC did not have effects on SOD and total glutathione activities, but decresed malone dialdehyde activity. In conclusion, these results suggest the possibility of BojungIkkiTang-Gamybang to protect brain cell or neuronal cell from damage induced by oxidative stress. And also suggest that related mechanisms are involved in malone dialdehyde activity.
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KEYWORD
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BojungIkkiTang, cell death, SOD, total glutathione, malone dialdehyde
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